BioHorizons vs MIS Implants: Which Mid-Range Brand Delivers More Value?
BioHorizons and MIS Implants represent the most compelling mid-range options in implant dentistry. Both offer premium-level clinical performance at significantly lower cost than Straumann or Nobel Biocare — but they achieve this through very different technologies.
BioHorizons (Birmingham, Alabama) is famous for the Laser-Lok® collar — precision-engineered micro-channels created by laser ablation that promote both bone and soft tissue attachment. This is a unique technology: while most implants focus on bone integration, Laser-Lok creates a biological seal at the gum line, potentially reducing peri-implantitis risk.
MIS Implants (Israel/Dentsply Sirona) competes with the B+ Surface — a nanostructured calcium phosphate surface that promotes rapid bone formation. MIS also offers the MGUIDE digital planning platform and one of the most versatile prosthetic libraries in its price range.
The $400 price gap ($1,500 vs $1,100) is meaningful for patients. The question is whether BioHorizons' unique Laser-Lok technology justifies the premium over MIS's strong overall value proposition.
Key Differences at a Glance
Full Specification Comparison
| Specification | BioHorizons | MIS Implants |
|---|---|---|
| Average Cost per Implant | $1,500 | $1,100 |
| Clinical Success Rate | 97.5% | 97.0% |
| Tier | Mid-Range | Mid-Range |
| Origin | USA | Israel |
| Material Type | Grade 4 Titanium with Laser-Lok® collar | Grade 4 / Grade 5 Titanium (Ti-6Al-4V) |
| Surface Technology | Laser-Lok® | B+ Surface |
| FDA Approval | FDA 510(k) Cleared — Tapered Internal and Tapered Pro systems | FDA 510(k) Cleared — V3, C1, Seven, and M4 implant systems |
| Warranty | Lifetime | Lifetime |
| Year Founded | 1994 | 1995 |
| Headquarters | Birmingham, Alabama, USA | Shlomi, Israel (Dentsply Sirona) |
Technology Comparison
BioHorizons Technology
Surface: Laser-Lok® — Precision-engineered micro-channels + RBT (Resorbable Blast Textured)
Material: Grade 4 Titanium with Laser-Lok® collar
Prosthetics: Cement-retained, Screw-retained, Overdenture, Multi-unit
MIS Implants Technology
Surface: B+ Surface — Sand-blasted & acid-etched with nanometer calcium phosphate
Material: Grade 4 / Grade 5 Titanium (Ti-6Al-4V)
Prosthetics: Cement-retained, Screw-retained, MGUIDE digital workflow, Overdenture
Who Is Each Brand Best For?
BioHorizons
Cost-conscious patients who still want advanced implant technology, general dentists placing routine implants, patients with adequate bone who want excellent value without compromising on science, and those specifically seeking soft-tissue attachment benefits to prevent bone loss around the implant collar.
MIS Implants
Price-sensitive patients who want a well-established implant brand with extensive clinical data, clinicians seeking a versatile system for both simple and moderately complex cases, and practices looking for a strong digital workflow integration through the MGUIDE platform.
Our Verdict
Choose BioHorizons if you value the unique soft-tissue attachment of Laser-Lok, are concerned about peri-implantitis long-term, or want an American-made implant with strong clinical evidence for bone preservation. Choose MIS Implants if you want excellent value at a lower price point, prefer digital planning through the MGUIDE system, or your clinician uses the MIS system.